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Negative Side Effects of CBD or hemp

cbd side effects

Numerous studies show that the benefits of taking CBD products are very promising. However, people tend to misunderstand these promising results as a reason to take more than they should without fully understanding the risks of doing so. People end up experiencing negative side effects that will take days to fully wear off.

This article explains the different side effects to look out for when taking CBD and how to avoid these from happening.

Side Effects of Taking CBD

Taking CBD oil can cause a variety of side effects whose severity may vary from one person to another. Here are some common side effects for CBD consumers:

  • Anxiety: People reported experiencing higher anxiety levels with CBD containing a higher concentration of THC.
  • Mood Changes: Although CBD is an alternative treatment for mood changes disorder, CBD also contains properties that can induce mood changes during interaction.
  • Dry Mouth: CBD interacts closely with salivary glands inside the mouth, eventually causing dry mouth.
  • Dizziness: CBD creates alteration in blood flow in the brain.
Additional side effects of taking CBD may include:
  • Vomiting
  • Appetite Changes
  • Fatigue
  • Diarrhea

There are still other side effects not mentioned by other CBD users. Since the experiences are relatively subjective to each person, researchers find it difficult to develop a more specific description of different symptoms.

Drugs and Other Ailments That Could Negatively Interact with CBD Oil

Some medications do not work well with CBD, eventually becoming more dangerous than beneficial. Although CBD might relieve some of the pain in these diseases and circumstances, it might do more harm than good, potentially diluting the benefits of the other medication in the body’s system.

The next part of this article which could not take CBD in their situation and the different drugs that might negatively react to the chemicals in CBD.

Liver Disease

CBD oil may contain liver enzymes, potentially placing a person at risk for liver inflammation. If the doctor prescribes CBD to the patient, he will also need to go through weekly checkups to ensure that the liver enzymes are normal.

Here are some combinations to watch out for because of their negative interaction with CBD:

  • Cytochrome P450 1A1: CBD can potentially slow down the breakdown of this medication in the liver, eventually increasing the side effects with other medications.
  • Clobazam: CBD might decrease the breakdown of clobazam in the liver.


Doctors do not recommend pregnant women take CBD. Studies showed that the chemicals in CBD pass through the placenta, making it very dangerous for the child in the mother’s womb. If mothers are still need a pain reliever, the doctor may recommend some alternative forms of treatment.

Anti-Arrhythmia drugs

The benefits of anti-arrhythmia drugs and CBD are still inconclusive, showing that it might have no conclusive evidence of any relief. Thus, if taken in unhealthy amounts, CBD might provide negative side effects that might dilute the benefits of the other drugs in the body.

However, small studies still support CBD use in treating heart arrhythmia. A study done on rats showed that administering CBD significantly reduced the number of arrhythmias after restoring blood supply to the test subjects.

Nevertheless, doctors still recommend taking other alternative treatments for CBD because of the lack of substantial evidence.

Other drugs and substances to look out for

  • Caffeine
  • Citalopram
  • Everolimus
  • Methadone
  • Carbamazepine
  • Warfarin
  • Lithium
  • Valproate

Does Taking CBD by Mouth Safer than Applying to Skin?

The severity of the side effects does not necessarily depend on the method of taking the CBD product. Regardless of whether the user chooses to take them through gummies or CBD oil, the proper dosage is important to ensure that the side effects will not be too severe.

Furthermore, there is still insufficient information to show whether applying CBD to the skin is relatively safer or whether the side effects would diminish.

However, some studies showed that taking the dosage by mouth is relatively safer in appropriate doses. Healthcare providers recommend at most 200 mg daily for 13 weeks. Some doctors might issue a more specific prescription that requires a larger dose but at longer intervals.

How to Prevent Side Effects from Happening

  • Listen to the Doctor

    Suppose the user is taking CBD as an alternative medicine for different ailments and diseases. In that case, it is important to follow these prescriptions to the letter to prevent any side effects from happening. The doctor should also properly warn the user of any potential side effects from happening and additional medicine to mitigate the severity.

  • Do Not Go Above Tolerance Level

    Overdose is a very dangerous state to be in because of the side effects and because it can lead to death. If the user is taking CBD for recreational purposes, they can mitigate these side effects by ensuring they do not take more than their tolerance level.

  • Only Buy FDA-Approved CBD Products

    The Food and Drug Administration is there to regulate anything consumers will intake by ensuring that it is safe to use with minimal side effects. Consider buying CBD products from those FDA-certified manufacturers and sellers to stay safe.

    Certified sellers would also present a label of the different chemicals inside the CBD products. The label would also show the potential effects and ways to mitigate them while consuming the product.


Despite the numerous health benefits of CBD products, an excess amount may cause numerous side effects that could potentially last for days. Some CBD products might not blend well with other medications some patients might use. To stay on the safe side, users should regularly consult with their healthcare providers for the right dosage and protocols to follow when they experience side effects.